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Wednesday, November 17, 2010

THE CRISIS



My heart feels cold, numb with emotions when i see patients who suffer from the SICKLE CELL ANAEMIA CRISIS. The pain they go through is unexplainable and unimaginable, their cries hit every nerve in my body and i wonder why these things happen.


I was in the Pediatrics wards the other day and i saw a 7 year old boy who was so irritable and in so much pain, he wouldn't even let us touch him. His mother was rolling in silent tears as she didn't want to let him know she was broken by his pain and tears.





The truth is that this SICKLE CELLS can be prevented in many ways and the most important way to fix this is by cross-checking blood groups compatibility with parents before they get married or get involved sexually. In our society now, it costs almost nothing to do a blood test, to find out your GENOTYPE and PHENOTYPE.



Sickle cell anemia is an inherited disease. People who have the disease inherit two copies of the sickle cell gene—one from each parent. The sickle cell gene causes the body to make abnormal hemoglobin. Hemoglobin is an iron-rich protein in red blood cells. It carries oxygen from the lungs to the rest of the body.

In sickle cell anemia, the hemoglobin sticks together after it delivers oxygen to the body's tissues. These clumps of hemoglobin are like liquid fibers. They cause the red blood cells to become stiff and have a sickle, or crescent, shape.

If you inherit one copy of the sickle cell gene (from one parent), you won't have sickle cell anemia. Instead, you'll have sickle cell trait.
People who have sickle cell trait usually have no symptoms and lead normal lives. However, some people may have medical complications.


People who have sickle cell trait also can pass the sickle cell gene to their children. The following image shows how two parents who have sickle cell trait can pass the sickle cell gene to their children.When both parents have a normal gene and an abnormal gene, each child has a 25 percent chance of inheriting two normal genes; a 50 percent chance of inheriting one normal gene and one abnormal gene; and a 25 percent chance of inheriting two abnormal genes.



Example of an Inheritance Pattern for Sickle Cell Trait

The image shows how sickle cell genes are inherited. A person inherits two copies of the hemoglobin gene-one from each parent. A normal gene will make normal hemoglobin (A). An abnormal (sickle cell) gene will make abnormal hemoglobin (S). When both parents have a normal gene and an abnormal gene, each child has a 25 percent chance of inheriting two normal genes; a 50 percent chance of inheriting one normal gene and one abnormal gene; and a 25 percent chance of inheriting two abnormal genes.




Virtually all of the major symptoms of sickle cell anemia are the direct result of the abnormally shaped, sickled red blood cells blocking the flow of blood that circulates through the tissues of the body. The tissues with impaired circulation suffer damage from lack of oxygen. Damage to tissues and organs of the body can cause severe disability in patients with sickle cell anemia. The patients endure episodes of intermittent "crises" of variable frequency and severity, depending on the degree of organ involvement.


The major features of sickle cell anemia include:
  • Fatigue and Anemia
  • Pain Crises
  • Dactylitis (swelling and inflammation of the hands and/or feet) and Arthritis
  • Bacterial Infections
  • Splenic Sequestration (sudden pooling of blood in the spleen) and Liver Congestion
  • Lung and Heart Injury
  • Leg Ulcers
  • Aseptic Necrosis and Bone Infarcts (death of portions of bone)
  • Eye Damage
  • Other Features     

The treatment of sickle cell anemia is designed according to which of the individual features of the illness are present. In general treatment is directed at the management and prevention of the acute manifestations as well as therapies directed toward blocking the red blood cells from stacking together. There is no single remedy to reverse the anemia. It is, therefore, important that family members have an optimal understanding of the illness and that communication with the doctors and medical personnel be maintained.

I woke up this morning with these thoughts in my heart and felt the need to communicate it to everyone and i am definitely glad i could accomplish it.

Lots of love.......  

18 comments:

  1. Sad but tru. pple in love neglect reality n suffer their offspring's. Most pple suffer for lack of knwledge but some ar aware yet they wanna test God in d name of faith. Even Wen they knw its wrong. If u knw u av an "S" pls avoid spouses with an "S" simple. God cannot b mocked.whatsoever a man sows same he'll reap. U cannot be AS + AS and av AA kids.Nanana! Don't b naïve oo.

    ReplyDelete
  2. i like your write up and i understand how you feel because i lost a younger sister to the disease.my prayers goes out to all siclers and pls lets stop bringing up more into the world by first knowing our genotype and doing the right thing.if you have the trait get married to a person withAA GENOTYPE.ODODO

    ReplyDelete
  3. My Blue Rose, I am proud of this write up that would save families, the nation and the entire would from the bite of the 'devil's teeth' as one of my patients once decribes it. Unfortunately, the feeling that love is supreme many a times beclouds hot lovers who act and believe they can damn the consequences. The devil's teeth only let go in hades. Thanks for telling us how to prevent it. Cheerio. OSB Adamolekun

    ReplyDelete
  4. I don't agree with the comment about testing God, if a union is of God then He has the power to make an SS person live a normal and fulfilled life. Sorry, but that is a very ignorant comment.
    Anyway, this is a well informed read, all this does is let people know that you can avoid complications by simply maintaining a healthy lifestyle. But coming from a place where we chow down starch for breakfast, why wouldn't it be a common health issue.
    Nice on Doc! Keep it up

    ReplyDelete
  5. Be warned!!! No amount of love can justify bringing a child into this world to suffer..KNOW YOUR GENOTYPE....

    ReplyDelete
  6. Very good, helpful. Weldone

    ReplyDelete
  7. Thanks, more of such info will save lives.

    ReplyDelete
  8. @kollegegoodboi (Quote: I don't agree with the comment about testing God, if a union is of God then He has the power to make an SS person live a normal and fulfilled life. Sorry, but that is a very ignorant comment.) Really???? Is god also going to pay the recurrent hospital bills???

    ReplyDelete
  9. sup doc! a little daily tip for those lovely peeps out there that are anemic pls. cos this will n i mean will go a long way in helping them out or would i say US

    ReplyDelete
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